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Nattokinase is a powerful soy-based enzyme that is extracted from a Japanese food called "natto." It has been used in Japan for over 1,000 years to boost cardiovascular and circulatory health. Nattokinase is highly rated for reducing blood clotting, as well as thinning the blood. There are many great benefits to the healthier blood flow supported by nattokinase, like increased oxygen levels in the extremities and normalized blood pressure.