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Resveratrol is a nutrient found in the skin of red grapes, as well as peanuts and some forms of chocolate. It is among the best anti-aging supplements because it boosts the body’s healing and defense mechanisms, causing them to renew damaged cells more quickly. It is highly recommended for its brain benefits: it activates AMPK, a key enzyme that is necessary for neuron health and energy. Resveratrol may also help sweep away unwanted protein deposits that contribute to cognitive decline.