Boost healthy circulation, from head to toe
Healthy blood circulation is essential for optimal health. When your heart is pumping strong and your blood is flowing as it should, your entire body benefits—from your head to your toes. That’s because every one of your vital organs relies on proper blood flow to deliver the oxygen and other essential nutrients it needs to function at peak levels. Ultimate Blood Flow Formula combines four researched nutrients—nattokinase, grape seed extract, green tea, and alpha lipoic acid—to promote healthy circulation and keep your blood flowing as it should.*
True Results:
- Promotes strong circulation*
- Supports proper blood clotting*
- Enhances blood vessel dilation*
- Protects against free-radical damage*
- Promotes healthy blood vessels*
How Ultimate Blood Flow Formula Works for You
Researchers have identified four powerful, natural, nutrients that support your circulation and blood vessels. And, these nutrients have been combined to create the most comprehensive supplement for healthy blood flow—Ultimate Blood Flow Formula.*
- Nattokinase (100 mg)
Nattokinase is an enzyme that’s derived from a Japanese food called natto that’s been heralded for its support of healthy blood flow. The power of the enzyme comes from its ability to both reduce excess fibrin and enhance plasmin production.*
Fibrin is a web-like protein that helps stop bleeding. Once it’s done its job, plasmin comes in to dissolve fibrin. However, as you age, your natural plasmin production slows down, resulting in excess fibrin in your arteries.*
Clinical studies have found that nattokinase supports healthy circulation and blood flow by dissolving fibrin. Research also indicates that nattokinase can help support healthy blood pressure levels.*
- Grape Seed Extract (400 mg)
Grapes have been heralded for their medicinal and nutritional value for thousands of years. The health benefits of grapes are thought to derive from chemicals within the fruit, particularly oligomeric proanthocyanidin complexes (OPCs), that have tremendous antioxidant power.*
Studies show that grape seed extract helps keep blood platelets an optimal consistency, to enhance blood flow. Furthermore, grape seed extract helps keep endothelial cells in your artery walls healthy, which maintains blood vessel flexibility and strength. These important benefits make grape seed extract a must for healthy circulation.*
- Green Tea Leaf Extract, 50% EGCG (200 mg)
The power of green tea comes mostly from its high content of epigallocatechin gallate, or EGCG. This amazing polyphenol works wonders for your circulation, in three key ways:*
- Maintains healthy flexibility and general well-being of your arteries. In two separate studies, green tea extract containing EGCG supported healthy Flow Mediated Dilation (FMD). FMD is the measure of how well your blood vessels dilate and move blood. The better your FMD, the better your blood flow and circulation. Very few natural solutions have been found to impact FMD, making green tea extract that much more extraordinary.*
- Maintains healthy cholesterol levels. Research has found that green tea consumption helps support healthy levels of LDL cholesterol in your blood and arteries. Healthy LDL levels means a clear path for your blood to flow.*
- Protects your arteries against free radicals. The EGCG in green tea acts as a beneficial antioxidant, keeping your artery walls strong against free radical attacks. Less free radicals mean healthier, more flexible arteries for better blood flow.*
Ultimate Blood Flow Formula gives you a full research dose of 200 mg daily of green tea extract, containing 50% EGCG. And the green tea is extremely low in caffeine…so low that you won't even know it's there.*
- Alpha Lipoic Acid (400 mg)
Alpha lipoic acid (ALA), also known as thioctic acid or just lipoic acid, is a powerful antioxidant.*
Antioxidants typically come in two varieties: water soluble and fat soluble. A few antioxidants, such as alpha lipoic acid, are both. That means the antioxidant can flow freely through the body and function in both watery and fatty tissue environments. This is one of the reasons that ALA is known as a “Universal Antioxidant.”*
The anti-aging benefits of alpha lipoic acid are well known. As a potent universal antioxidant, it helps to fight free radicals throughout the body, reducing oxidative stress, protecting your arteries, and even improving the vascular reactivity (function) of your veins and arteries.*
Research Results
Nattokinase for Healthy Circulation
An open-label, self-controlled clinical trial found that nattokinase had a positive impact on healthy circulation by reducing levels of fibrin in the blood.* Read More
Grape Seed Extract To Support Proper Platelet Viscosity*
In an 8-week, double-blind, randomized control trial, researchers found that grape seed extract supported healthy platelet function by prolonging occlusion (closure times).* Read More
Green Tea Leaf Extract for Improved Blood Flow and Cholesterol Support*
A 2-week study found that green tea consumption supported endothelial health and improved flow-mediated dilation (FMD) in adults, compared to baseline.* Read More
Alpha Lipoic Acid to Reduce Oxidative Stress*
In a randomized, double-blind placebo controlled study, researchers found ALA supplementation reduced oxidative stress and had a positive impact on HDL cholesterol.* Read More
Note: If you are taking blood thinning medications, you should consult your healthcare professional before taking Ultimate Blood Flow Formula.
Research Results
Featured Ingredient: Nattokinase
A randomized, double-blind, placebo-controlled human clinical trial explored the impact of nattokinase on heart health. 73 study participants with blood pressure concerns were divided into two groups. One group ingested 2,000 FU (the equivalent of 100 mg) of nattokinase orally daily for 8 weeks. The other group received a placebo. Researchers found that the group that received nattokinase supplementation experienced a reduction in both systolic and diastolic blood pressure.1*
Featured Ingredient: Grape Seed Extract
In an 8-week, double-blind, randomized control trial of post-menopausal women, researchers explored the impact of grape seed extract (GSE) on platelet function. Researchers divided the 17 study participants into two groups. One group received 400 mg of grape seed extract. The other group was given a placebo. At the conclusion of the trial, the results showed that the group that was given grape seed extract experienced prolonged occlusion (closure times) after ADP-stimulation. This effect was significant on day 1, increasing ADP-stimulated closure time by 23.7% after 2 hours and 14.2% after 6 hours, post consumption. In addition, GSE, but not placebo, was associated with a strong trend for increasing ADP-stimulated closure time after 8 weeks.2*
A randomized, placebo-controlled, study investigated the impact of grape seed extract on oxidized LDL cholesterol levels. 61 healthy subjects were divided into three groups. One group received 200 mg of grape seed extract daily. A second group received 400 mg of grape seed extract per day. The third group received a placebo. After 12 weeks, researchers discovered that the group that was given 400 mg of grape seed extract significantly reduced oxidized LDL cholesterol.3*
Featured Ingredient: Green Tea Leaf Extract
A 2-week study of 20 young healthy smokers explored the impact of green tea consumption on endothelial health and flow-mediated dilation (FMD). The adults consumed 8 grams of green tea each day containing 3.2% EGCG (the equivalent of 256 mg daily of EGCG.) At the conclusion of the study, researchers found improved endothelial function and FMD compared to baseline.4*
The acute effect of green tea consumption was investigated in a study of 14 healthy smokers. On three separate occasions, trial subjects took either: 6 grams of green tea, 125 mg of caffeine, or hot water. Flow-mediated dilation (FMD) of the brachial artery was measured before each intervention and 30, 90, and 120 minutes afterward. Researchers found that flow mediated dilation increased significantly with the tea, indicating green tea’s beneficial effect on endothelial function.5*
A double-blind, placebo-controlled study was conducted with 240 Japanese men and women. Researchers divided the subjects into two groups. One group received 583 mg daily of catechins, comprised of 17.2% EGCG (the equivalent of 100 mg of EGCG) for 12 weeks. The control group received 96 mg of catechins per day. At the end of the trial, researchers discovered that the group that received the higher dose of catechins had better support for healthy LDL cholesterol and systolic blood pressure than control. The larger catechins dose also resulted in a greater decrease in body weight, BMI, body fat ratio, body fat mass, waist circumference, hip circumference, visceral fat, and subcutaneous fat more than the control.6*
Featured Ingredient: Alpha Lipoic Acid
In a 4-week randomized control of people with blood sugar concerns, the impact of ALA on oxidative stress was explored. A total of 14 patients were randomly assigned to the two groups.*
One group received 400 mg daily of alpha lipoic acid. The other received a placebo. At the end of the study researchers found reduced markers of oxidative stress and improved HDL cholesterol in the group that was given ALA.7*
1 Kim JY et al. 2008 Aug;31(8):1583-8.
2 Shenoy SF et al. 2007;121(3):431-2. Epub 2007 Oct 24.
3 J Nutr Sci Vitaminol (Tokyo). 2007 Apr;53(2):174-82.
4 Circ J. 2006 Aug;70(8):1052-7.
5 Alexopoulos N et al. 2008 Jun;15(3):300-5.
6 Nageo T et al. 2007 Jun;15(6):1473-83.
7 Arch Gerontol Geriatr. 2009;49 Suppl 1:129-33.
Featured Ingredient: Nattokinase
A randomized, double-blind, placebo-controlled human clinical trial explored the impact of nattokinase on heart health. 73 study participants with blood pressure concerns were divided into two groups. One group ingested 2,000 FU (the equivalent of 100 mg) of nattokinase orally daily for 8 weeks. The other group received a placebo. Researchers found that the group that received nattokinase supplementation experienced a reduction in both systolic and diastolic blood pressure.1*
Featured Ingredient: Grape Seed Extract
In an 8-week, double-blind, randomized control trial of post-menopausal women, researchers explored the impact of grape seed extract (GSE) on platelet function. Researchers divided the 17 study participants into two groups. One group received 400 mg of grape seed extract. The other group was given a placebo. At the conclusion of the trial, the results showed that the group that was given grape seed extract experienced prolonged occlusion (closure times) after ADP-stimulation. This effect was significant on day 1, increasing ADP-stimulated closure time by 23.7% after 2 hours and 14.2% after 6 hours, post consumption. In addition, GSE, but not placebo, was associated with a strong trend for increasing ADP-stimulated closure time after 8 weeks.2*
A randomized, placebo-controlled, study investigated the impact of grape seed extract on oxidized LDL cholesterol levels. 61 healthy subjects were divided into three groups. One group received 200 mg of grape seed extract daily. A second group received 400 mg of grape seed extract per day. The third group received a placebo. After 12 weeks, researchers discovered that the group that was given 400 mg of grape seed extract significantly reduced oxidized LDL cholesterol.3*
Featured Ingredient: Green Tea Leaf Extract
A 2-week study of 20 young healthy smokers explored the impact of green tea consumption on endothelial health and flow-mediated dilation (FMD). The adults consumed 8 grams of green tea each day containing 3.2% EGCG (the equivalent of 256 mg daily of EGCG.) At the conclusion of the study, researchers found improved endothelial function and FMD compared to baseline.4*
The acute effect of green tea consumption was investigated in a study of 14 healthy smokers. On three separate occasions, trial subjects took either: 6 grams of green tea, 125 mg of caffeine, or hot water. Flow-mediated dilation (FMD) of the brachial artery was measured before each intervention and 30, 90, and 120 minutes afterward. Researchers found that flow mediated dilation increased significantly with the tea, indicating green tea’s beneficial effect on endothelial function.5*
A double-blind, placebo-controlled study was conducted with 240 Japanese men and women. Researchers divided the subjects into two groups. One group received 583 mg daily of catechins, comprised of 17.2% EGCG (the equivalent of 100 mg of EGCG) for 12 weeks. The control group received 96 mg of catechins per day. At the end of the trial, researchers discovered that the group that received the higher dose of catechins had better support for healthy LDL cholesterol and systolic blood pressure than control. The larger catechins dose also resulted in a greater decrease in body weight, BMI, body fat ratio, body fat mass, waist circumference, hip circumference, visceral fat, and subcutaneous fat more than the control.6*
Featured Ingredient: Alpha Lipoic Acid
In a 4-week randomized control of people with blood sugar concerns, the impact of ALA on oxidative stress was explored. A total of 14 patients were randomly assigned to the two groups.*
One group received 400 mg daily of alpha lipoic acid. The other received a placebo. At the end of the study researchers found reduced markers of oxidative stress and improved HDL cholesterol in the group that was given ALA.7*
1 Kim JY et al. 2008 Aug;31(8):1583-8.
2 Shenoy SF et al. 2007;121(3):431-2. Epub 2007 Oct 24.
3 J Nutr Sci Vitaminol (Tokyo). 2007 Apr;53(2):174-82.
4 Circ J. 2006 Aug;70(8):1052-7.
5 Alexopoulos N et al. 2008 Jun;15(3):300-5.
6 Nageo T et al. 2007 Jun;15(6):1473-83.
7 Arch Gerontol Geriatr. 2009;49 Suppl 1:129-33.
Supplement Facts:
Serving size: 2 capsules
Servings per bottle: 30 (1 month supply)
Each bottle contains: 60 Capsules
Suggested Use: Take 2 capsules daily,or as directed by your physician.
NOTE: If you take Coumadin® (warfarin) or other blood thinners, or are pregnant or nursing, consult your physician prior to taking.
| Each serving contains: | Amount Per Serving | % Daily Value |
|---|---|---|
| Alpha Lipoic Acid | 400 mg | * |
| Grape Seed extract (95% polyphenols) |
400 mg | * |
| Green Tea leaf extract (50% EGCG) |
200 mg | * |
| Nattokinase♦ (from soy) | 100 mg | * |
| *Daily Value (DV) not established |
Other Ingredients: Gelatin, microcrystalline cellulose, magnesium stearate and methacrylic acid copolymer N.F. (enteric coating).
CONTAINS: Soy
♦NattoSEB® is a registered trademark of Specialty Enzymes and Biotechnologies, Chino, CA.